Sensitivity and Specificty of Transrectal Ultrasonography in Diagnosing Prostate Cancer

Objective: To determine the sensitivity and specificity of detecting prostate cancer by TRUS when compared to histopathology report. Subjects and Methods: This cross-sectional analytical study was carried out within six months from October 2010 to March 2011 in the Department of Radiology/Histopathology, Shaikh Zayed Hospital Lahore. One hundred and ten patients, age above 40 years having abnormal DRE finding and positive serum PSA value were included in the study. Patients with abnormal hemostasis, unfit for TRUS guided biopsy were excluded from the study. All patients underwent transrectal ultrasonography in evaluation of sonographically suspicious malignant lesions of prostate and histological confirmation of these lesions by taking TRUS guided transrectal biopsy were carried out. Conclusion: TRUS continues to play an important role in the evaluation of the prostate when malignancy is suspected. Although the optimal method of prostate biopsy is controversial, ultrasound is critical in ensuring accurate sampling of the gland.